He was the grandson of John Henry Isherwood, squire of Marple Hall and Wyberslegh Hall, Cheshire, and he included among his ancestors the Puritan judge John Bradshaw, who signed the death warrant of King Charles I and served for two years as Lord President of the Council, effectively President of the English Republic. He was the elder son of Francis Edward Bradshaw Isherwood (1869–1915), known as Frank, a professional soldier in the York and Lancaster Regiment, and Kathleen Bradshaw Isherwood, nee Machell Smith (1868–1960), the only daughter of a successful wine merchant. Isherwood was born in 1904 on his family's estate in Cheshire near Stockport in the north-west of England.
His best-known works include Goodbye to Berlin (1939), a semi-autobiographical novel which inspired the musical Cabaret, A Single Man (1964) adapted as a film by Tom Ford in 2009, and Christopher and His Kind (1976), a memoir which 'carried him into the heart of the Gay Liberation movement'.
Christopher William Bradshaw Isherwood (26 August 1904 – 4 January 1986) was an Anglo-American novelist, playwright, screenwriter, autobiographer, and diarist.